{"id":2797,"date":"2022-01-17T18:43:29","date_gmt":"2022-01-17T09:43:29","guid":{"rendered":"https:\/\/yoshida-lab.bs.teu.ac.jp\/?p=2797"},"modified":"2022-01-17T18:43:30","modified_gmt":"2022-01-17T09:43:30","slug":"%e3%83%a1%e3%83%81%e3%83%ab%e5%8c%96%e3%81%ab%e3%82%88%e3%82%8avegf-i-motif%e3%81%8c%e5%ae%89%e5%ae%9a%e5%8c%96%e3%81%99%e3%82%8b%e3%81%93%e3%81%a8%e3%82%92%e6%98%8e%e3%82%89%e3%81%8b%e3%81%ab","status":"publish","type":"post","link":"https:\/\/yoshida-lab.bs.teu.ac.jp\/?p=2797","title":{"rendered":"\u30e1\u30c1\u30eb\u5316\u306b\u3088\u308aVEGF i-motif\u304c\u5b89\u5b9a\u5316\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u8ad6\u6587\u304cBiochem. Biophys. Res. Commun.\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\uff01"},"content":{"rendered":"\n<p>\u30d2\u30c8\u30b2\u30ce\u30e0DNA\u306b\u304a\u3044\u3066\u30b0\u30a2\u30cb\u30f3\u304c\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u308b\u9818\u57df\u3067\u306f\u30b0\u30a2\u30cb\u30f3\u56db\u91cd\u9396\u69cb\u9020\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u4e00\u65b9\u3001\u305d\u306e\u76f8\u88dc\u9396\u306b\u306f\u30b7\u30c8\u30b7\u30f3\u304c\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u9818\u57df\u3067\u306f\u7279\u6b8a\u306a\u56db\u91cd\u9396\u69cb\u9020\u3067\u3042\u308bi-motif\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u30b0\u30a2\u30cb\u30f3\u56db\u91cd\u9396\u3084i-motif\u69cb\u9020\u5f62\u6210\u306f\u8ee2\u5199\u5236\u5fa1\u306a\u3069\u69d8\u3005\u306a\u751f\u547d\u73fe\u8c61\u306b\u95a2\u4e0e\u3057\u3066\u304a\u308a\u307e\u3059\u3002\u672c\u7814\u7a76\u3067\u306f\u3001<em>VEGF<\/em>\u306e\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u4e2d\u3067\u5f62\u6210\u3055\u308c\u308bi-motif\u69cb\u9020\u4e2d\u306eCpG\u3092\u30e1\u30c1\u30eb\u5316\u3059\u308b\u3068\u3001\u305d\u306e\u5b89\u5b9a\u6027\u304c\u4e0a\u6607\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u4eca\u5f8c\u3001\u30e1\u30c1\u30eb\u5316<em>VEGF<\/em> i-motif\u3092\u4ecb\u3057\u305f\u65b0\u305f\u306a\u8ee2\u5199\u5236\u5fa1\u6a5f\u69cb\u306e\u89e3\u660e\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u306a\u304a\u3001\u672c\u7814\u7a76\u306f\u6771\u4eac\u8fb2\u5de5\u5927\u5b66\u306e\u6c60\u888b\u6559\u6388\u3068\u5171\u540c\u3067\u5b9f\u65bd\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u25a0\u767a\u8868\u8ad6\u6587<\/p>\n\n\n\n<p>\u8457\u8005\uff1aKimura K., Oshikawa D., Ikebukuro K., Yoshida W.<br>\u30bf\u30a4\u30c8\u30eb\uff1aStabilization of <em>VEGF<\/em> i-motif structure by CpG methylation<br>\u63b2\u8f09\u96d1\u8a8c\uff1aBiochem. Biophys. Res. Commun. (2022) In press<br>URL: <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X22000742\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0006291X22000742<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30d2\u30c8\u30b2\u30ce\u30e0DNA\u306b\u304a\u3044\u3066\u30b0\u30a2\u30cb\u30f3\u304c\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u308b\u9818\u57df\u3067\u306f\u30b0\u30a2\u30cb\u30f3\u56db\u91cd\u9396\u69cb\u9020\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u4e00\u65b9\u3001\u305d\u306e\u76f8\u88dc\u9396\u306b\u306f\u30b7\u30c8\u30b7\u30f3\u304c\u8c4a\u5bcc\u306b\u542b\u307e\u308c\u3066\u304a\u308a\u3001\u3053\u308c\u3089\u9818\u57df\u3067\u306f\u7279\u6b8a\u306a\u56db\u91cd\u9396\u69cb\u9020\u3067\u3042\u308bi-motif\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u3089\u30b0\u30a2\u30cb\u30f3 [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"sns_share_botton_hide":"","vkExUnit_sns_title":"","_vk_print_noindex":"","sitemap_hide":"","vkExUnit_EyeCatch_disable":"","_veu_custom_css":"","veu_display_promotion_alert":"","vkexunit_cta_each_option":"","vk-ltc-link":"","vk-ltc-target":"0","twitterCardType":"","cardImageID":0,"cardImage":"","cardTitle":"","cardDesc":"","cardImageAlt":"","cardPlayer":"","cardPlayerWidth":0,"cardPlayerHeight":0,"cardPlayerStream":"","cardPlayerCodec":"","_lightning_design_setting":{"layout":"default"},"footnotes":""},"categories":[16],"tags":[],"class_list":["post-2797","post","type-post","status-publish","format-standard","hentry","category-16"],"veu_head_title_object":{"title":"","add_site_title":""},"_links":{"self":[{"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2797","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2797"}],"version-history":[{"count":3,"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2797\/revisions"}],"predecessor-version":[{"id":2800,"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2797\/revisions\/2800"}],"wp:attachment":[{"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2797"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2797"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yoshida-lab.bs.teu.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2797"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}