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February 16th, 2018 / Last updated : February 8th, 2023 吉田亘 Uncategorized

Our research paper about G4 clusters has been published in Scientific Reports.

Yoshida W.*, Saikyo H., Nakabayashi K., Yoshioka H., Bay D.H., Iida K., Kawai T., Hata K., Ikebukuro K., Nagasawa K., Karube I. Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand. Scientific Reports (2018) 8, 3116 (*Corresponding author)

December 15th, 2017 / Last updated : February 22nd, 2018 吉田亘 Uncategorized

Our Students Receive Outstanding Performance Awards at the 9th Competition of the Consortium of Universities in Hachioji

Ms. Natsumi Taka and Ms. Yuumi Hatsushika (Yoshida Lab. in the Graduate School Bionics Program ) received Outstanding Performance Awards in the Consortium of Universities in Hachioji competition held on December 9 , 2017. Ms. Taka gave an oral presentation entitled “Direct Sensing of Cancer Genomic DNA for Cancer Diagnostics,” and Ms. Hatsushika gave a […]

November 13th, 2017 / Last updated : February 22nd, 2018 吉田亘 Uncategorized

Development of a global DNA methylation bio-sensing system for cancer diagnostics

We developed a bio-sensing system for global DNA methylation levels that can be applied to cancer diagnostics. The paper has been published in Analytica Chimica Acta (Vol. 990, p. 168-173, 2017)1. DNA methylation of cytosine in CpG dinucleotides has important biological roles in regulation of gene expression. In cancer cells, hypomethylation has been reported in […]

July 28th, 2017 / Last updated : February 8th, 2023 吉田亘 Uncategorized

Our research paper has been published in Analytica Chimica Acta.

Yoshida W.*, Baba Y., Banzawa K., Karube I. A quantitative homogeneous assay for global DNA methylation levels using CpG-binding domain- and methyl-CpG-binding domain-fused luciferase Anal. Chim. Acta (2017) 990, 168-173

June 27th, 2017 / Last updated : February 8th, 2023 吉田亘 Uncategorized

Our research paper has been published in BMC Molecular Biology.

Bay D.H., Busch A., Lisdat F., Iida K., Ikebukuro K., Nagasawa K., Karube I., Yoshida W.* Identification of G-quadruplex structures that possess transcriptional regulating functions in the Dele and Cdc6 CpG islands BMC Molecular Biology (2017) 18, 17

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