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June 26th, 2018 / Last updated : February 8th, 2023 吉田亘 Uncategorized

Our research paper about methylated VEGF G4 has been published in BBA General Subjects!

Yoshida W.*, Terasaka M., Laddachote S., Karube I.Stabilization of G-quadruplex structure on vascular endothelial growth factor gene promoter depends on CpG methylation site and cation type.BBA General Subjects (2018) 1862, 1933 (*Corresponding author)

March 13th, 2018 / Last updated : March 10th, 2020 吉田亘 Uncategorized

Outstanding Reviewer Award (Biosensors and Bioelectronics, BBA – General Subjects)

Dr. Yoshida has been received Outstanding Reviewer Award from Biosensors and Bioelectronics, and BBA – General Subjects. Reviewers who are within the top 10th percentile of reviewers, in terms of the number of manuscript reviews completed in the last two years, are awarded.

February 27th, 2018 / Last updated : March 10th, 2020 吉田亘 Uncategorized

Lab T-shirt!

Izzul-kun designed our lab T-shirt. A monovalent cation (positive ion) is required to form G-quartet structure. Thank you for cool T-shirt!  

February 19th, 2018 / Last updated : February 22nd, 2018 吉田亘 Uncategorized

Identification of G-quadruplex clusters on human genomic DNA

We identified 9,651 G-quadruplex clusters on human genomic DNA. The paper has been published in Scientific Reports.1 G-quadruplex (G4) is a non-canonical DNA structure that has been found in several regulatory regions, such as telomeres, CpG islands and promoters. The identification of G4-forming sequences is important in elucidating the function of G4 structures on genomic […]

February 16th, 2018 / Last updated : February 8th, 2023 吉田亘 Uncategorized

Our research paper about G4 clusters has been published in Scientific Reports.

Yoshida W.*, Saikyo H., Nakabayashi K., Yoshioka H., Bay D.H., Iida K., Kawai T., Hata K., Ikebukuro K., Nagasawa K., Karube I. Identification of G-quadruplex clusters by high-throughput sequencing of whole-genome amplified products with a G-quadruplex ligand. Scientific Reports (2018) 8, 3116 (*Corresponding author)

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